論文名稱: 轉阻放大器用於生物晶片訊號處理之研究
[摘要]
利用微機電製程技術可用以製造微結構供量測微小的物質,例如DNA或者病毒數量之量測, 這些產生的訊號通常亦相當微弱需要放大電路將此類訊號放大以供後級處理。
BJT元件為電流控制元件,適合用作電流量測之輸入級與高頻率電路之應用,但其製程較為
特殊且成本較高。單級放大電路的頻寬與放大增益值為Trade-off之規格。結合以上之條件 ,
本論文欲嘗試利用成本較低的MOS製程,將電流訊號放大電路晶片化,避免大電阻以增加
其可攜性;又因FET為壓控元件且先天上noise 雜訊較大對微小訊號之判讀造成不小的影響
,本文嘗試設計與分析一轉阻放大器作為高轉阻與高頻寬的放大器電路的可行性。
本文以帶有簡單回授電路之CMOS電流鏡結構為起點,作為電流偵測端與電流轉電壓訊號放
大器,將訊號轉換成較普遍之電壓訊號。以TSMC 0.35 CMOS製程對此電流訊號放大作模擬
,結果符合所欲達到的頻寬10MHz與轉阻值1M 。

 
[摘要]
MEMS technology could be applied on bio-chips for measuring and detecting
micro object. Generally the signal is too small and needs amplifying for next
processing. Currently there are many op amp ICs could be used for amplifying
these signals. But considering larger bandwidth, much simpler circuits, much
simpler manufacture process than BJT, and portability, we try to develop a TIA
circuit to condition the signal of the architecture by CMOS process and avoid
a large resistor to construct a high transresistance and wide bandwidth
amplifier circuit.
The structure of current mirror with simple feedback circuit is employed to
design the transimpedance amplifier to translate current signals to voltage
signals. The circuit is simulated with TSMC 0.35 CMOS process condition. The
results satisfy basic requirements. The bandwidth is larger than 10MHz,and
transimpedance is 1M ohm .

 
[論文目次]
中文摘要                                                                i
ABSTRACT                                                               ii
誌謝                                                                   iii
CONTENTS                                                             iv  
Table Contents                                                                 v
Figure Contents                                                                 vi
Chapter 1 INTRODUCTION                                                          1
1.1 Introduction                                                                     1
1.1.1 DNA SEQUENCING                                                                   1
1.1.2 Virus Counting Chips                                                                     4
1.2 Thesis Organization                                                                     6
Chapter 2 THE TRANSIMPEDANCE AMPLIFIER                                                   7
2.1 The types of amplifiers                                                                   7
2.2 Transimpedance Amplifier                                                              11 
2.2.1 Transimpedance Amplifier Characteristics                                                                  11
2.2.2 Typical Transimpedance Architectures                                                                 12
Chapter 3 WIDEBAND & HIGH Rm TRANSIMPEDANCE AMPLIFIER
CIRCUIT DESCRIPTION                                                       20
3.1 Introduction                                                                  20
3.1.1 Negative Feedback System                                                                 21
3.1.2 Multistage amplifier                                                                     22
3.1.3 Noise Analysis                                                                    28
3.2 Circuit Design and Analysis                                                                  32
Chapter 4 SIMULATION RESULTS AND DISSCUSSION                                        34
4.1 Circuit Simulation                                                                   34
Chapter 5 CONCLUSION                                                       43
REFERENCES                                                            45

 
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